Help CureSHANK with your Giving Tuesday and Year-End generosity. Make your tax-deductible gift today!

MATCH UNLOCKED

A matching gift of $50,000 means every December donation will go twice as far in accelerating treatments for Phelan-McDermid syndrome. Together, your year-end support will help bridge the gap from lab to clinical trials and bring hope to families now. Let’s finish the year strong—for science, for care, for those counting on CureSHANK.

Give hope. Fuel breakthroughs. Bring treatments closer.

When the year ends, it’s easy to think it’s all been said and done—but for the CureSHANK community, your support now matters more than ever. This is the moment where your generosity can turn discoveries in the lab into real treatments that change lives.

Why give now?

Breakthroughs are within reach as scientists make real progress toward therapies for Phelan-McDermid syndrome. Your gift powers the critical steps—preclinical studies, trial design, and translating discoveries into treatments—ensuring that promising science moves quickly toward life-changing therapies for children and adults living with PMS.

Accelerate Science

This December, your gift can do twice the good. Thanks to a $50,000 matching challenge, every dollar you give will be doubled—but only for a limited time. Don’t miss this chance to accelerate research and bring life-changing treatments closer than ever.

maximize Your Impact

Children and adults with Phelan-McDermid syndrome are losing precious time while waiting for treatments that don’t yet exist. Your support today fuels the breakthroughs of tomorrow—bringing us closer to therapies that can preserve skills, restore abilities, and give families hope for a brighter future.

CHANGE THE FUTURE

this is a hard look

This short video offers a raw, unfiltered look at daily life with Phelan-McDermid syndrome. Through Abby and her son Darus’s story, you’ll see the relentless challenges families face—and the urgent need for treatments that can change lives. CureSHANK is funding research to bring real therapies within reach. Your support today can help turn rare smiles into everyday moments.

What Difference You Can Make

Thank you to our generous donors!