Together, we can turn promising science into real solutions for families.
Make your Giving Tuesday gift today!
Unlock our match!
We have an early bird fundraising goal of $20,000 in donations between now and Tuesday, December 2. Reaching this goal will unlock a dollar for dollar match up to $20,000 from a generous CureSHANK donor. Will you help us unlock the match?
Together, today.
CureSHANK is at an inflection point — for the very first time, we may have multiple treatment options available to our families within a few years. From small molecules to gene therapies, to antisense oligonucleotides, we are within reach of the therapies we have been so desperately hoping for. There is still critical work to be done to get them across the finish line. CureSHANK is at the forefront of that effort, but we can’t do it alone.
We need your help. Let’s do this together, today!
this is a hard look
This short video offers a raw, unfiltered look at daily life with Phelan-McDermid syndrome. Through Abby and her son Darus’s story, you’ll see the relentless challenges families face—and the urgent need for treatments that can change lives. CureSHANK is funding research to bring real therapies within reach. Your support today can help turn rare smiles into everyday moments.
help us get the word out
Can you help us reach more people to increase Phelan-McDermid syndrome awareness and funds for cutting-edge science? It’s easy! Click the button below to download the graphic, and add your personal touch with a photo or image that you choose. Simply click and hover your image over the landscape image on the right side to pop it into the frame. Then, post your unique graphic to your social media channels with a link to www.cureSHANK.org/give2025.
Don’t forget to tag us @CureSHANK and use our hashtag #TogetherToday!
WHY GIVE NOW?
Breakthroughs are within reach as scientists make real progress toward therapies for Phelan-McDermid syndrome. Your gift powers the critical steps—preclinical studies, trial design, and translating discoveries into treatments—ensuring that promising science moves quickly toward life-changing therapies for children and adults living with PMS.
Accelerate Science
We have a lofty goal to reach $50,000 in donations by the end of Giving Tuesday, December 2. If we reach it, a generous donor has agreed to match every dollar up to $20,000. Will you help us unlock our match? Don’t miss this limited time opportunity — the clock runs out at 11:59 p.m. P
unlock our match
Children and adults with Phelan-McDermid syndrome are losing precious time while waiting for treatments that don’t yet exist. Your support today fuels the breakthroughs of tomorrow—bringing us closer to therapies that can preserve skills, restore abilities, and give families hope for a brighter future.