2026 Year-End Giving
In 2026, a landmark prevalence study* confirmed what our community has long suspected: Phelan-McDermid syndrome (PMS) may be twice as common as previously estimated.
This finding underscores the urgency of accelerating life-transforming treatments for PMS. And together, we can accelerate promising science toward therapies for people living with PMS.
CureSHANK unites families, researchers, industry, and advocates to drive scientific advancements. We plan to make significant strides in our mission in 2027, and we invite you to be a part of it.
Donate today to support our work to advance meaningful treatments — and ultimately a cure — for individuals living with Phelan-McDermid syndrome.
*The PMS prevalence study was funded by Neuren Pharmaceuticals, CureSHANK, and Seaver Autism Center
Your gift will help CureSHANK unite families, scientists, clinicians, companies and supporters to build the research, resources and partnerships needed to accelerate PMS treatments.
Support our work to accelerate Meaningful PMS therapies in 2027!
Double Your Impact
Thanks to a generous donor, for a limited time, all gifts will be matched!
Together, today.
A better future for PMS families is within reach. For the very first time, multiple precision medicines are in development, with two already in Phase II or III trials.
From small molecules to gene therapies, to antisense oligonucleotides, we are within reach of the therapies we have been so desperately hoping for.
There is still critical work to be done to get them across the finish line. CureSHANK is at the forefront of that effort, but we can’t do it alone.
WHY GIVE NOW?
Advances in genetics and therapeutic development are creating new opportunities to pursue meaningful treatments. Breakthroughs are within reach as scientists make real progress toward therapies for Phelan-McDermid syndrome.
Your gift powers the critical steps—preclinical studies, trial design, and translating discoveries into treatments—ensuring that promising science moves quickly toward life-changing therapies for children and adults living with PMS.
Accelerate Science
We are thrilled to share that, for a limited time, every donation made will be matched dollar for dollar, thanks to a generous CureSHANK donor.
Your support will help us unlock the full match and double the impact of every gift.
Will you help us reach our goal?
DOUBLE YOUR IMPACT
CureSHANK is at the forefront of research and treatment development for Phelan-McDermid syndrome. We have built a thriving research and development ecosystem designed to help promising programs move more efficiently toward patients.
Your support today fuels the breakthroughs of tomorrow — bringing us closer to therapies that can give families hope for a brighter future.
CHANGE THE FUTURE
help us get the word out
Can you help us reach more people to raise Phelan-McDermid syndrome awareness and funds for life-changing science?
It’s easy! Click the button to access the graphic, and add your personal touch with a photo or image that you choose. Simply drag and drop your image(s) over the circular images on the right side to swap out the photo. Then, post your unique graphic to your social media channels with a link to www.cureshank.org/give2026.
Don’t forget to tag us @CureSHANK so we can amplify your post!
